Pathophysiology is actually the study of changes of normal biochemical, mechanical, and physical functions, in the human body which are caused by a disease or any other abnormal syndrome.
This post will describe the pathophysiology of urticaria. You might think that this should be only useful for medical students or professionals but if you are understand it, you can go about urticaria treatment in a better way.
Urticaria is caused by the release of histamines, bradykinin, leukotriene C4, and some other vasoactive fluids by the mast cells (which are a part of our defense mechanism). This can involve capillary or membrane damage as well. When these fluids e.g. histamines are released into the dermis, the rashes of urticaria appear on the skin, which are itchy and usually red in color. Physical urticaria is usually caused by physical stimuli, whereas in chronic urticaria the causes are usually unknown.
Do not miss the next post upcoming week which has some great tips for avoiding urticaria.