Allergic Urticaria | Urticaria Allergy

Allergic urticaria is a severe skin condition characterized by the presence of welts that itch intensely. It is caused by an allergic reaction, an infection, or a nervous condition. It is also known as urticaria allergy. Sometimes, it has very similar symptoms to Urticaria Pigmentosa Mastocytosis.

Mast cells play an important role in the allergic reaction that causes allergic urticaria. These cells are widespread in human skin. Histamine and other pro-inflammatory substances are released from these mast cells into the skin and tissues in response to the binding of allergen-bound IgE antibodies to high affinity cell surface receptors. Besides mast cells, basophils and certain other inflammatory cells are also believed to release histamines and other mediators and are thought to play an important role, especially in allergic urticarial diseases.

Allergic Urticaria Treatment

Urticaria allergy treatment can be a challenge even for a physician. The following suggestions can help patients find relief from the itchiness and swelling.

  • All allergic urticaria patients should avoid certain drugs, such as aspirin, codeine, opiates, procaine, alcohol, and polymyxin B. Patients should also avoid hot baths and vigorous rubbing after bathing. These drugs and activities can release histamines, which can aggravate the situation and cause extreme itching and flushing. 
  • Different foods containing tartrazine or meats preserved with benzoates can trigger allergy. Therefore, you should not consume such food items or confectionery.
  • Keep the affected area cool with a fan or an ice pack.
  • Oppressive treatment of allergic urticaria is carried out by administering antihistaminic drugs, such as Chloropheneramine (Avil) triprolidine hydrochloride, Actidil and Cyproheptadine hydrochloride (Periactin). Consume according to the doctor's prescription or the dose frequency should be adjusted to provide adequate coverage for 24 hours.
  • The drugs mentioned above may cause varying degrees of drowsiness; therefore driving, operating machines, and performing other jobs that require mental vigilance should be avoided as long as the effect persists. 
  • If your urticaria allergy is not responsive to oral antihistamines, then you may have to be treated with injections of adrenaline or steroids, especially if you are having trouble breathing due to swelling in the airway.

 

P.S. (from Dr. Gary M. Levin, M.D. & Surgeon)
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