Angioedema and Lupus

This article is about the correlation of angioedema and lupus, and angioedema precedes the lupus or systemic lupus erythematosus (SLE). For a better understanding of the connection between angioedema and lupus, I am going to define these two terms separately.

Angioedema, sometimes referred to as Quincke edema, is an allergic skin disorder typically characterized by itchless and painless swelling involving the skin, dermis, subcutaneous tissues, the mucous membranes, and occasionally, the viscera.

Lupus or lupus erythematosus is a category for a collection of diverse diseases with similar underlying problems with immunity. It is, actually, an autoimmune connective tissue disease that can affect heart, lungs or any other part of the body. Just like any other autoimmune disease, our immune system attacks the body's cells and tissue, resulting in itching, inflammation and sometime tissue damage. Symptoms of lupus like syndrome can affect joints, skin, kidneys, blood cells, heart, and lungs. There are 4 main types of lupus - discoid lupus erythematosus, systemic lupus erythematosus, drug-induced lupus erythematosus, and neonatal lupus erythematosus. Systemic lupus erythematosus is the most common and serious form of this disease.

In extremely rare cases, systematic lupus erythematosus diagnosis was preceded by the angioedema. Systematic lupus erythematosus is actually a systematic autoimmune disease that can affect any part of the human body. It damages the tissues and causes inflammation because of the attack of immune system on the body tissues and cells.

A delayed diagnosis of angioedema can result a compromise in the upper way and in some cases it may lead to lupus erythematosus as well. This usually happens in cases where the patient is suffering from acquired angioedema which occurs due to an acquired deficiency of C1 Inhibitors. Some patients may also show an association with pruritic erythematous rash.

Certain powerful steroids and antihistamines can be opted for the treatment. However, it is recommended that you must consult a qualified doctor for proper diagnosis and treatment of angioedema and lupus.


P.S. (from Dr. Gary M. Levin, M.D. & Surgeon)
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